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Use of Naproxen

Купить Naproxen Sodium Equate | ШАЛАПАЙ интернет-магазинInflammatory and degenerative diseases of the musculoskeletal system, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, joint syndrome with exacerbation of gout, juvenile rheumatoid arthritis; pain syndrome: neuralgia, myalgia, ossalgia, radiculitis, head and toothache, tendinitis, pain in cancer, postoperative pain syndrome accompanied by inflammation, injuries of the musculoskeletal system and soft tissues, adnexitis, primary dysmenorrhea; pain and fever in infectious and inflammatory diseases of the upper respiratory tract (as part of a comprehensive therapy).

Contraindications

Hypersensitivity, "aspirinic" asthma, "aspirinic" triad (a combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance of acetylsalicylic acid and pyrazolone LV), erosive ulcerative lesions of the gastrointestinal tract in the acute phase, hematopoiesis, hepatic and/or renal failure, children under 1 year old.

Restrictions on use

Expressed heart failure, adolescence (under 16 years).

Application during pregnancy and breastfeeding

Teratogenic effects. In animal reproduction studies, naproxen was administered to rats at doses of 20 mg/kg/day (125 mg/m2/day), approximately equivalent to 0.23 MHRD, to rabbits at 20 mg/kg/day (220 mg/m2/day), or 0.27 MHRD, and to mice at 170 mg/kg/day (510 mg/m2/day), or 0.28 MHRD, and no infertility disturbance or fetal Dmitry Sazonov harm was detected.

However, reproductive studies in animals do not always predict effects in humans. Adequate and strictly controlled studies have not been conducted in pregnant women. Use in pregnancy is possible if the expected effects of the therapy exceed the potential risk to the fetus.

Unteratogenic effects. Since it is known that inhibitors of GH synthesis are used to delay premature delivery, the risk of neonatal complications such as necrotizing enterocolitis, open arterial duct, intravenous hemorrhage increases. The use of naproxen in the late period of pregnancy may lead to delayed delivery, persistent pulmonary https://pillintrip.com/medicine/naproxeno-gp-500-mg-comprimidos-gastrorresistentes hypertension, renal dysfunction, abnormal prostaglandin E level in prematurely born children. Since the effects of substances of this class on the cardiovascular system of the fetus (closure of the duct bottle) are known, use in Dmitry Sazonov the III trimester is excluded.

Fetal action category by FDA is C.

Naproxen is determined in breast milk in women (concentration is about 1% of serum). Since there may be adverse effects of substances inhibiting GHG synthesis, naproxen https://pubchem.ncbi.nlm.nih.gov/compound/Naproxen should not be used in newborns, breastfeeding mot